Wayne A. Moore
Senior Software Programmer
Wayne Moore has led software development effort in the Herzenberg Laboratory for the past twenty years. Moore designed and implemented the initial (PDP-11) system used to collect and analyze FACS data (ca.1980) as well as subsequent programs ("FACS/Desk") on the DEC-VAX 780. In 1983, he developed FACS/Desk, a comprehensive data acquisition, management and analysis system. Since that time, FACS/Desk has been running continuously, with periodic updates at Stanford and other locations worldwide. It has served hundreds of biologists and provides access to several hundred gigabytes of FACS data, which is currently stored online or in its online-accessible tape archive.
Moore is currently designing and building an innovative internet-based system that will replace FACS/Desk with state of the art communications software and methods for cataloging and retrieving data according to annotations that define the context in which the data was collected. He is also a highly competent mathematician and statistician and will introduce new methods for visualizing interpreting FACS data in the new system.
Parks, D. R., Roederer, M., and Moore, W. A. 2006. A new "Logicle" display method avoids deceptive effects of logarithmic scaling for low signals and compensated data. Cytometry A 69:541.
Herzenberg, L. A., Tung, J., Moore, W. A., Herzenberg, L. A., and Parks, D. R. 2006. Interpreting flow cytometry data: a guide for the perplexed. Nature immunology 7:681.
Tung, J. W., Parks, D. R., Moore, W. A., and Herzenberg, L. A. 2004. New approaches to fluorescence compensation and visualization of FACS data. Clin Immunol 110:277.
Tung, J. W., Parks, D. R., Moore, W. A., and Herzenberg, L. A. 2004. Identification of B-Cell Subsets: An Exposition of 11-Color (Hi-D) FACS Methods. In Methods Mol Biol, p. 37.
Roederer, M., Treister, A., Moore, W. A., and Herzenberg, L. A. 2001. Probability binning comparison: A metric for quantitating univariate distribution differences. Cytometry 45:37.
Roederer, M., Moore, W. A., Treister, A., Hardy, R. R., and Herzenberg, L. A. 2001. Probability binning comparison: a metric for quantitating multivariate distribution differences. Cytometry 45:47.
De Rosa, S. C., Zaretsky, M. D., Dubs, J. G., Roederer, M., Anderson, M., Green, A., Mitra, D., Watanabe, N., Nakamura, H., Tjioe, I., Deresinski, S. C., Moore, W. A., Ela, S. W., Parks, D., Herzenberg, L. A., and Herzenberg, L. A. 2000. N-acetylcysteine (NAC) replenishes glutathione in HIV infection. European Journal of Clinical Investigation 30:841.
Herzenberg, L. A., Moore, W. A., and De Rosa, S. C. 1999. Estimation of missing values. Lancet 354:Correspondence.
Bigos, M., Parks, D. R., Moore, W. A., and Herzenberg, L. A. 1994. Pattern sorting: a computer-controlled multidimensional sorting method using k-d trees. Cytometry 16:357.
Staal, F. J. T., Roederer, M., Israelski, D. M., Bubp, J., Mole, L. A., McShane, D., Deresinski, S. C., Ross, W., Sussman, H., Raju, P. A., Anderson, M. T., Moore, W., Ela, S. W., Herzenberg, L. A., and Herzenberg, L. A. 1992. Intracellular glutathione levels in T cell subsets decrease in HIV infected individuals. AIDS Res. Human Retrov. 8:305.
Staal, F. J., Roederer, M., Bubp, J., Mole, L. A., Anderson, M. T., Raju, P. A., Israelski, D. M., Deresinski, S. C., Moore, W. A., and Herzenberg, L. A. 1992. CD20 expression is increased on B lymphocytes from HIV-infected individuals [published erratum appears in J Acquir Immune Defic Syndr 1992;5(9):956]. Journal of Acquired Immune Deficiency Syndromes 5:627.
Moore, W. and Kautz, R. 1986. Data analysis for flow cytometry. In D.M. Weir, Herzenberg, L. A., Blackwell, C. C., and Herzenberg, L. A., eds., The Handbook of Experimental Immunology, 4th edn., p. 30.1 Blackwell Scientific Publications, Ltd., Edinburgh.
Herzenberg, L. A., Stall, A. M., Lalor, P. A., Sidman, C., Moore, W. A., and Parks, D. R. 1986. The Ly-1 B cell lineage. Immunological Reviews 93:81.